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Drug Repositioning for P-Glycoprotein Mediated Co-Expression Networks in Colorectal Cancer

13 Aug 2020

Abstract excerpt

Colorectal cancer (CRC) is one of the most fatal types of cancers that is seen in both men and women. CRC is the third most common type of cancer worldwide. Over the years, several drugs are developed for the treatment of CRC; however, patients with advanced CRC can be resistant to some drugs. P-glycoprotein (P-gp) (also known as Multidrug Resistance 1, MDR1) is a well-identified membrane transporter protein...

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PMID: 32903699
DOI: 10.3389/fonc.2020.01273

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