Article
Identification and structural comparison of deleterious mutations in nsSNPs of ABL1 gene in chronic myeloid leukemia: a bio-informatics study.
Journal of biomedical informatics - 1 Aug 2008
George Priya Doss C, Sudandiradoss C, Rajasekaran R, Purohit Rituraj, Ramanathan K, Sethumadhavan Rao
Abstract excerpt
Single nucleotide polymorphism (SNP) serve as frequent genetic markers along the chromosome. They can, however, have important consequences for individual susceptibility to disease and reactions to medical treatment. Also, genetics of the human phenotype variation could be understood by knowing the functions of these SNPs. Currently, a vast literature exists reporting possible associations between SNPs and...
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