Article

Topsentinol L Trisulfate, a new Marine Natural Product, that Targets Basal-like and Claudin-low Breast Cancers

2020-04-18

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> Breast cancer is a heterogeneous disease. Genomic studies have revealed five different intrinsic subtypes - Luminal A, Luminal B, HER2-enriched, Claudin-low, and Basal-like. Patients diagnosed with Basal-like or Claudin-low breast cancer (BL-CL) suffer from poor prognosis and limited treatment options. Hence, there is an urgent need to identify a new therapeutic lead that ca...

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Literature Corpus work: 61956a49-067e-5821-a8ec-de113d85e1ae
DOI: 10.1101/2020.04.17.047555

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