Article

Identification Of Pathogenic Mutations And Application Of Polygenic Risk Scores In Early-Onset Diabetes Patients

2024-12-02

Abstract excerpt

<title>Abstract</title> <p><bold>Background: </bold>Maturity-onset Diabetes of the Young (MODY) presents a diagnostic challenge, with a large proportion of cases lacking identifiable genetic mutations, which could lead to sub-optimal medical treatment and, subsequently, a decline in patients’ life quality. This study investigates the utility of polygenic risk score (PRS) in distinguishing monogenic diabetes from...

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Literature Corpus work: 619139bd-85cd-5623-b2b6-cbf69b0bcc82
DOI: 10.21203/rs.3.rs-5361647/v1

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