Article

Identification Of Pathogenic Mutations And Application Of Polygenic Risk Scores To Differentiate MODY Patients From Other Diabetes Types

2024-03-21

Abstract excerpt

<title>Abstract</title> <p>Maturity-onset Diabetes of the Young (MODY) presents a diagnostic challenge, with a large proportion of cases lacking identifiable genetic mutations. This study investigates the genetic basis of MODY in a Latvian cohort comprising 66 suspected MODY families, contrasted with 177 non-diabetic controls. Employing panel-based and whole-genome sequencing (WGS), we identified 22 pathogenic mu...

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Literature Corpus work: be547aca-39f5-5a40-9339-a154c2687d2a
DOI: 10.21203/rs.3.rs-4109118/v1

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