Article

Aberrant activated APOBEC3B is associated with p53 mutant-driven refractory/relapsed Diffuse Large B-cell Lymphoma

2020-10-15

Abstract excerpt

<h4>Background: </h4> Although treatment of diffuse large B-cell lymphoma (DLBCL) has progressed considerably in recent years, treatment failure still occurs in about 40% of patients who are refractory/relapse. Recent studies suggest that TP53 mutation may be an important cause of refractory/relapse in DLBCL, but the cause of TP53 mutation remains unclear. MethodsIn the present study, the correlation between TP53...

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Literature Corpus work: 618eae77-db16-5194-af91-85fc3094f345
DOI: 10.21203/rs.3.rs-91694/v1

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