Article
Determination of metal ion transport rate of human ZIP4 using stable zinc isotopes
2024-05-20
Abstract excerpt
The essential microelement zinc is absorbed in the small intestine mainly by the zinc transporter ZIP4, a representative member of the Zrt/Irt-like protein (ZIP) family. ZIP4 is reportedly upregulated in many cancers, making it a promising oncology drug target. To date, there have been no reports on the turnover number of ZIP4, which is a crucial missing piece of information needed to better understand the transpo...
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Identifiers and source
- Literature Corpus work
- 61202c24-3959-5912-bf61-be46b961256e
- DOI
- 10.1101/2024.05.20.594990