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Regulation and function of <i>Zip4</i> , the acrodermatitis enteropathica gene

19 Nov 2008

Abstract excerpt

The SLC39A (solute carrier 39A) [ZIP (Zrt-Irt-like protein)] family consists of 14 members which are thought to control zinc uptake into the cytoplasm. Among these, ZIP4 is known to be particularly important for zinc homoeostasis. Mutations in this gene cause acrodermatitis enteropathica, a rare recessive-lethal human genetic disorder. In the present paper, our studies of the regulation and function of the mouse...

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PMID: 19021533
DOI: 10.1042/bst0361242

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Regulation and function of <i>Zip4</i> , the acrodermatitis enteropathica genePMID 19021533Read ↗

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