Article

Hypermetabolic state is associated with circadian rhythm disruption in mouse and human cancer cells

2023-11-13

Abstract excerpt

Crosstalk between cellular metabolism and circadian rhythms is a fundamental building block of multicellular life, and disruption of this reciprocal communication could be relevant to degenerative disease, including cancer. Here, we investigated whether maintenance of circadian rhythms depends upon specific metabolic pathways, particularly in the context of cancer. We found that in adult mouse fibroblasts, ATP lev...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 6119c5ea-3d0b-5ded-9926-73eff115c587
DOI: 10.1101/2023.11.08.566310

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Hypermetabolic state is associated with circadian rhythm disruption in mouse and human cancer cellsDOI 10.1101/2023.11.08.566310Read

Cancer Clocks Out for Lunch: Disruption of Circadian Rhythm and Metabolic Oscillation in CancerSemantic proximity Read

The Circadian Clock Regulates Metabolic Phenotype Rewiring Via HKDC1 and Modulates Tumor Progression and Drug Response in Colorectal CancerSemantic proximity Read

Metabolism and cancer: the circadian clock connection.Semantic proximity Read

MYC disrupts transcriptional and metabolic circadian oscillations in cancer and promotes enhanced biosynthesisSemantic proximity Read

The Cancer Clock Is (Not) Ticking: Links between Circadian Rhythms and CancerSemantic proximity Read

The metabolic significance of peripheral tissue clocksSemantic proximity Read

Bridging the gap: advancing cancer cell culture to reveal key metabolic targetsSemantic proximity Read

A cancer ubiquitome landscape identifies metabolic reprogramming as target of Parkin tumor suppressionSemantic proximity Read

Perturbational profiling of a cell-line model of tumorigenesis by using metabolic measurementsSemantic proximity Read

Circadian Rhythm Disruption Promotes Lung Tumorigenesis.Semantic proximity Read

Circadian clocks and metabolism.Semantic proximity Read

Sexual dimorphism in the response to chronic circadian misalignment on a high-fat dietSemantic proximity Read