Article
Metabolism and cancer: the circadian clock connection.
Nature reviews. Cancer - 1 Dec 2009
Sahar Saurabh, Sassone-Corsi Paolo
Abstract excerpt
Circadian rhythms govern a remarkable variety of metabolic and physiological functions. Accumulating epidemiological and genetic evidence indicates that the disruption of circadian rhythms might be directly linked to cancer. Intriguingly, several molecular gears constituting the clock machinery have been found to establish functional interplays with regulators of the cell cycle, and alterations in clock function...
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