Article

Fluid shear stress modulates endocytic pathways and junctional targeting of tumor-derived extracellular vesicles in endothelial cells

2026-05-05

Abstract excerpt

Breast cancer is the most common malignancy in women, with triple-negative breast cancer (TNBC) representing the most aggressive subtype and carrying a poor metastatic prognosis. Metastasis requires tumor cells to cross the endothelial barrier, a process facilitated by tumor-derived extracellular vesicles (EVs), which can disrupt vascular integrity. Fluid shear stress (FSS), generated by blood flow, shapes endothe...

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Identifiers and source

Literature Corpus work: 60fc7838-da5c-5a71-8eae-1182335caad8
DOI: 10.64898/2026.05.01.721946

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