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Article

The contribution of silencer variants to human diseases.

2024-05-18

Abstract excerpt

Although disease-causal genetic variants have been found within silencer sequences, we still lack a comprehensive analysis of the association of silencers with diseases. Here, we profiled GWAS variants in 2.8 million candidate silencers across 97 human samples derived from a diverse panel of tissues and developmental time points, using deep learning models. We show that candidate silencers exhibit strong enrichmen...

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Identifiers and source

Literature Corpus work
60e00416-7ebe-51d8-95ef-303b39152fa5
DOI
10.1101/2024.05.17.24307558
Open publication

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The contribution of silencer variants to human diseases.DOI 10.1101/2024.05.17.24307558
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