Article

Transcriptomic Profiling of Old Age Sarcoma Patients using TCGA RNA-seq data

2025-01-07

Abstract excerpt

Sarcoma is a rare malignancy with poor prognosis, especially in older patients (≥ 65 years) as seen in our preliminary analysis and some previous studies. Moreover, these patients have limited treatment options due to therapy-associated adverse effects and altered tumor micro-environment, which could be associated with their lower prognosis. Studying the underlying biology that drives cancer progression in these p...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 60df3e57-df70-5bc4-8d72-362d05ca66b6
DOI: 10.1101/2025.01.03.631189

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Transcriptomic Profiling of Old Age Sarcoma Patients using TCGA RNA-seq dataDOI 10.1101/2025.01.03.631189Read

Proteomic Features of Adolescents and Young Adults with Soft Tissue TumoursSemantic proximity Read

Transcriptomic-Based Classification Identifies Prognostic Subtypes and Therapeutic Strategies in Soft Tissue SarcomasSemantic proximity Read

Identification of a survival-related signature for sarcoma patients through integrated transcriptomic and proteomic profiling analysesSemantic proximity Read

Integrated single-cell analysis reveals heterogeneity and therapeutic insights in osteosarcomaSemantic proximity Read

Identification and characterization of aging/senescence-induced genes in osteosarcoma and predicting clinical prognosisSemantic proximity Read

Comprehensive analysis of potential cellular communication networks in advanced osteosarcoma using single-cell RNA sequencing dataSemantic proximity Read

Gene Expression Classifier Reveals Prognostic Osteosarcoma Microenvironment Molecular Subtypes.Semantic proximity Read

Genetic and environmental reprogramming of the sarcoma epigenome.Semantic proximity Read

Single-cell RNA sequencing reveals the immune microenvironment landscape of osteosarcoma before and after chemotherapySemantic proximity Read

Integrative multi-omics analysis reveals molecular subtypes and tumor evolution of synovial sarcomaSemantic proximity Read

Whole-Exome Analysis and Osteosarcoma: A Game Still Open.Semantic proximity Read

Abnormal signal pathways and tumor heterogeneity in osteosarcomaSemantic proximity Read