Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Gene Expression Classifier Reveals Prognostic Osteosarcoma Microenvironment Molecular Subtypes.

Frontiers in immunology - 1 Jan 2021

Song Yi-Jiang, Xu Yanyang, Deng Chuangzhong, Zhu Xiaojun, Fu Jianchang, Chen Hongmin, Lu Jinchang, Xu Huaiyuan, Song Guohui, Tang Qinglian, Wang Jin

Abstract excerpt

Osteosarcoma (OSA) is the most common bone malignancy and displays high heterogeneity of molecular phenotypes. This study aimed to characterize the molecular features of OSA by developing a classification system based on the gene expression profile of the tumor microenvironment. Integrative analysis was performed using specimens and clinical information for OSA patients from the TARGET program. Using a matrix...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bone Neoplasms
Share to Cancer-Associated Fibroblasts

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to CD8-Positive T-Lymphocytes

Share to Fibrosis

Share to Gene Regulatory Networks

Share to Lymphocytes, Tumor-Infiltrating

Share to Osteosarcoma

Share to Tumor Microenvironment

Source

Open in PubMed Open full text

Identifiers

PMID: 33959121
DOI: 10.3389/fimmu.2021.623762
PMCID: PMC8093635

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Gene Expression Classifier Reveals Prognostic Osteosarcoma Microenvironment Molecular Subtypes.PMID 33959121Read ↗

Comprehensive investigation of tumor immune microenvironment and prognostic biomarkers in osteosarcoma through integrated bulk and single-cell transcriptomic analysisSemantic proximity Read ↗

Tumor microenvironment phenotypes and prognostic evaluation tools for osteosarcoma characterized by different prognostic outcomes and immunotherapy responses.Semantic proximity Read ↗

Classification of Osteosarcoma Based on Immunogenomic ProfilingSemantic proximity Read ↗

Identification of a Novel Prognostic Gene Signature From the Immune Cell Infiltration Landscape of OsteosarcomaSemantic proximity Read ↗

Construction of an Immune-Related lncRNA Signature That Predicts Prognosis and Immune Microenvironment in Osteosarcoma PatientsSemantic proximity Read ↗

Signature based on immune-related LncRNA can predict overall survival of osteosarcoma patientsSemantic proximity Read ↗

Single-cell RNA sequencing reveals the immune microenvironment landscape of osteosarcoma before and after chemotherapySemantic proximity Read ↗

A diagnostic signature developed based on the necroptosis-related genes and its association with immune infiltration in osteosarcomaSemantic proximity Read ↗

Development of a Risk Model and Genotyping Patterns Based on Disulfidptosis-Related lncRNAs to Predict Prognosis and Immune Landscape in Osteosarcoma.Semantic proximity Read ↗

Multi-omics analysis reveals cuproptosis and mitochondria-based signature for assessing prognosis and immune landscape in osteosarcomaSemantic proximity Read ↗

Ferroptosis-related lncRNAs guiding osteosarcoma prognosis and immune microenvironmentSemantic proximity Read ↗

EMT-related gene classifications predict the prognosis, immune infiltration, and therapeutic response of osteosarcomaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.