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Personalising pain management in advanced cancer: is KCNJ6 A1032G associated with methadone response?

2022-03-07

Abstract excerpt

Opioids are the therapeutic agents of choice to manage moderate to severe pain in patients with advanced cancer, however the unpredictable inter-individual response to opioid therapy remains a challenge for clinicians. While studies are few, the KCNJ6 gene is a promising target for investigating genetic factors that contribute to pain and analgesia response. This is the first association study on polymorphisms in...

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Literature Corpus work
60b57269-1f88-5674-8e2b-f92799ebc8db
DOI
10.21203/rs.3.rs-1371929/v1
Open publication

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