Optimising opioids for cancer pain : investigating the basis of inter-individual analgesic response and side-effect profile

Abstract excerpt

There is significant inter-individual variation in response to morphine in terms of analgesia and side-effects. In recent years there has been growing interest in the possibility that genetic factors may play a role in variability in morphine response. The aims of this thesis were to develop a clinically relevant method of defining response to morphine, to investigate how multiple clinical and genetic factors may...

Topics

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• Analgesics, Opioid
• Morphine
• Pain
• Pain Measurement
• Receptors, Opioid
• Receptors, Opioid, delta
• Receptors, Opioid, kappa
• Receptors, Opioid, mu

Identifiers and source

Literature Corpus work

7cfe3e9e-d339-5d8d-9f9e-2e00d2f0cd85

DOI

10.25560/9252