Article

A miRNA screen procedure identifies garz as an essential factor in adult glia functions and validates Drosophila as a beneficial 3Rs model to study glial functions and GBF1 biology

2020-07-23

Abstract excerpt

Invertebrate glia performs most of the key functions controlled by mammalian glia in the nervous system and provides an ideal model for genetic studies of glial functions. To study the influence of adult glial cells in ageing we have performed a genetic screen in Drosophila using a collection of transgenic lines providing conditional expression of micro-RNAs (miRNAs). Here, we describe a methodological algorithm...

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Literature Corpus work: 60aaa17e-8c5f-5c98-97fa-5d2c344a0f61
DOI: 10.12688/f1000research.23154.2

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