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Article

miR-31 mutants reveal continuous glial homeostasis in the adult Drosophila brain.

The EMBO journal - 2 May 2017

Foo Lynette Caizhen, Song Shilin, Cohen Stephen Michael

Abstract excerpt

The study of adult neural cell production has concentrated on neurogenesis. The mechanisms controlling adult gliogenesis are still poorly understood. Here, we provide evidence for a homeostatic process that maintains the population of glial cells in the Drosophila adult brain. Flies lacking microRNA miR-31a start adult life with a normal complement of glia, but transiently lose glia due to apoptosis. miR-31a...

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Identifiers

PMID: 28320737
DOI: 10.15252/embj.201695861
PMCID: PMC5412881

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