Article

DNA Nanoflower Enables Controlled Co-Delivery of Antisense Oligodeoxynucleotide and Doxorubicin for Anti-breast Cancer Treatment

2025-02-21

Abstract excerpt

Doxorubicin (DOX), an anthracycline antibiotic, is widely used to treat a range of solid tumors and hematological malignancies. However, its clinical application in breast cancer is hindered by toxic side effects and the development of multidrug resistance (MDR). Enhancing the selective targeting of DOX and overcoming MDR are critical to improving treatment efficacy. Here, we present a DNA nanoflower (DNF)-based d...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 60669e70-6528-5621-9fb3-5c53d059d711
DOI: 10.22541/au.174017526.63124569/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

DNA Nanoflower Enables Controlled Co-Delivery of Antisense Oligodeoxynucleotide and Doxorubicin for Anti-breast Cancer TreatmentDOI 10.22541/au.174017526.63124569/v1Read

Theranostic DNA nanostructure based on phenotype-specific activation of antisense oligonucleotides.Semantic proximity Read

Expanding the Chemical Repertoire of DNA Nanomaterials Generated by Rolling Circle AmplificationSemantic proximity Read

Enhancing Breast Cancer Therapy: Nanocarrier-Based Targeted Drug DeliverySemantic proximity Read

Construction of Graphene Oxide Probes Loaded with Antisense Peptide Nucleic Acid and Doxorubicin for Regulating Telomerase Activity and Inducing Apoptosis of Cancer CellsSemantic proximity Read

Reversing Multidrug Resistance by Multiplexed Gene Silencing for Enhanced Breast Cancer ChemotherapySemantic proximity Read

Molecular avenues in targeted doxorubicin cancer therapySemantic proximity Read

The Bcl-2 silencing with an Antisense Oligonucleotide: Increase early ApoptosisSemantic proximity Read

Rolling circle amplification-templated DNA nanotubes show increased stability and cell penetration ability.Semantic proximity Read

Cancer Fighting SiRNA-RRM2 Loaded NanorobotsSemantic proximity Read

Advances in Cancer Treatment through Nanotheranostics and Emerging TherapiesSemantic proximity Read

Harnessing DNA Tetrahedral Nanoparticles: A Novel Strategy for Co- delivery of OTUD6B siRNA and DOX Against TNBC Growth and ProgressionSemantic proximity Read

Engineering circular guide RNA and CRISPR-Cas13d-encoding mRNA for the RNA editing of <i>Adar1</i> in triple-negative breast cancer immunotherapySemantic proximity Read