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Article

Rolling circle amplification-templated DNA nanotubes show increased stability and cell penetration ability.

Journal of the American Chemical Society - 15 Feb 2012

Hamblin Graham D, Carneiro Karina M M, Fakhoury Johans F, Bujold Katherine E, Sleiman Hanadi F

Abstract excerpt

DNA nanotubes hold promise as scaffolds for protein organization, as templates of nanowires and photonic systems, and as drug delivery vehicles. We present a new DNA-economic strategy for the construction of DNA nanotubes with a backbone produced by rolling circle amplification (RCA), which results in increased stability and templated length. These nanotubes are more resistant to nuclease degradation, capable of...

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PMID: 22283197
DOI: 10.1021/ja2107492

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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