Article

3C Based DNA Hybridization Method for Chromosomal Translocation Screening

2021-10-12

Abstract excerpt

<h4>Background: </h4> DNA probes have been widely used as diagnostic tools for chromosomal translocations in malignancies. PCR-based methods often fail to detect translocations such as MYC/TRD in chronic lymphocytic leukemia. In addition, microscopic techniques cannot be helpful due to size detection limitations. This study sought to design a screening tool using immobilized ssDNA probes on a nitrocellulose membra...

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Literature Corpus work: 60089c35-2d20-57f9-b698-b2ee709ae0b6
DOI: 10.21203/rs.3.rs-864665/v2

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