Article

Rare, pathogenic germline variants in <i>Fanconi Anemia</i> genes increase risk for squamous lung cancer

2018-02-22

Abstract excerpt

<h4>Purpose</h4> Lung cancer is the leading cause of cancer deaths worldwide, with substantially better prognosis in early stage as opposed to late stage disease. Identifying genetic factors for lung squamous carcinoma (SqCC) risk will enable their use in risk stratification, and personalized intensive surveillance, early detection, and prevention strategies for high-risk individuals. <h4>Study Design and Partici...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 5ffba7f1-4d91-5dc5-864e-d4b1651b3065
DOI: 10.1101/269837

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Rare, pathogenic germline variants in <i>Fanconi Anemia</i> genes increase risk for squamous lung cancerDOI 10.1101/269837Read

Rare, Pathogenic Germline Variants in Fanconi Anemia Genes Increase Risk for Squamous Lung CancerSemantic proximity Read

Rare germline deleterious variants increase susceptibility for lung cancer.Semantic proximity Read

Inherited genetic risk factors in young-onset lung cancerSemantic proximity Read

Landscape of germline pathogenic variants in patients with dual primary breast and lung cancer.Semantic proximity Read

Analyses of rare predisposing variants of lung cancer in 6,004 whole genomes in Chinese.Semantic proximity Read

Germline rare deleterious variant load alters cancer risk, age of onset and tumor characteristicsSemantic proximity Read

Inherited rare, deleterious variants in <i>ATM</i> increase lung adenocarcinoma riskSemantic proximity Read

Rare variants of large effect in BRCA2 and CHEK2 affect risk of lung cancer.Semantic proximity Read

AVENGERS: Analysis of Variant Effects using Next Generation sequencing to Enhance <i>BRCA2</i> StratificationSemantic proximity Read

Ancestry-Specific Predisposing Germline Variants in CancerSemantic proximity Read

Ancestry-specific predisposing germline variants in cancer.Semantic proximity Read

Whole-genome sequencing of East Asian lung cancers reveals new germline pathogenic variants.Semantic proximity Read