Article

Development of tools to explore the fundamentals of axonemal dynein heavy chain biology and improve the efficiency of genome editing

2020-01-01

Abstract excerpt

Motile cilia are microtubule based projections that assist in the movement of fluid over the surface of cells, such as in the respiratory epithelium, or of cells through a fluid, such as in sperm. Ciliary movement is driven by axonemal dyneins (ADs), large molecular complexes which contain long heavy chain ATPase motor subunits. The stability of ADs has been shown to be dependent on multiple cytoplasmically locali...

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Literature Corpus work: 5fe3eb71-0646-5177-95ea-04bbf98bc688
DOI: 10.7488/era/177

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