Article

PFKM inhibits doxorubicin-induced cardiotoxicity by enhancing oxidative phosphorylation and glycolysis

2022-05-31

Abstract excerpt

<h4>Background: </h4> Heart failure (HF) is a global pandemic which affects about 26 million people. PFKM (Phosphofructokinase, Muscle), catalyzing the phosphorylation of fructose-6-phosphate, plays a very important role in cardiovascular diseases. However, the effect of PFKM in glycolysis and HF remains to be elucidated. <h4>Materials: </h4> and methods: H9c2 rat cardiomyocyte cells were used in this study. Cells...

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Literature Corpus work: 5fd7dda8-b65e-5b71-9175-e3ac190d7f32
DOI: 10.21203/rs.3.rs-1664969/v1

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