Article

Antioxidant Response Activating nanoParticles (ARAPas) localize to atherosclerotic plaque and locally activate the Nrf2 pathway

2021-09-17

Abstract excerpt

Atherosclerotic disease is the leading cause of death world-wide with few novel therapies available despite the ongoing health burden. Redox dysfunction is a well-established driver of atherosclerotic progression; however, the clinical translation of redox-based therapies is lacking. One of the challenges facing redox-based therapies is their targeted delivery to cellular domains of redox dysregulation. In the cur...

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Literature Corpus work: 5fab6430-2997-54fa-94e3-b43af8157ae0
DOI: 10.1101/2021.09.16.460323

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