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Cell Line Models of Molecular Subtypes of Colorectal Cancer.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2018

Mooi Jennifer K, Luk Ian Y, Mariadason John M

Abstract excerpt

Colorectal cancer (CRC) is a genetically diverse disease necessitating the need for well-characterized and reproducible models to enable its accurate investigation. Recent genomic analyses have confirmed that CRC cell lines accurately retain the key genetic alterations and represent the major molecular subtypes of primary CRC, underscoring their value as powerful preclinical models. In this chapter we detail the...

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PMID: 29589298
DOI: 10.1007/978-1-4939-7765-9_1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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