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Investigating the suitability of in vitro cell lines as models for the major subtypes of epithelial ovarian cancer

13 Feb 2023

Abstract excerpt

Epithelial ovarian cancer (EOC) is the most fatal gynaecological malignancy, accounting for over 200,000 deaths worldwide per year. EOC is a highly heterogeneous disease, classified into five major histological subtypes–high-grade serous (HGSOC), clear cell (CCOC), endometrioid (ENOC), mucinous (MOC) and low-grade serous (LGSOC) ovarian carcinomas. Classification of EOCs is clinically beneficial, as the various...

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PMID: 36861035
DOI: 10.3389/fcell.2023.1104514

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