Article

The role of Nuclear Lamins in regulating the circadian molecular clockwork : daily oscillations and response to mechanical stimulation

2019-01-01

Abstract excerpt

Circadian rhythms are evolutionarily conserved ~24h biological cycles in physiology, metabolism, and behaviour, including locomotor activity. Musculoskeletal cells contain cell-autonomous, self-sustainable circadian clocks; synchronised by a central clock located in the suprachiasmatic nuclei. The nuclear lamina underlies the nuclear envelope and consists of type-V intermediate filament proteins called lamins. Lam...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 272fc6da-ae61-5ce3-ad0a-8e5c46a383a6
DOI: 10.17638/03045875

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

The role of Nuclear Lamins in regulating the circadian molecular clockwork : daily oscillations and response to mechanical stimulationDOI 10.17638/03045875Read

Lamin A/C Mechanotransduction in Laminopathies.Semantic proximity Read

Changes in Chromatin Organisation and Mechanotransduction Mediated by Mutant Lamins in Laminopathies.Semantic proximity Read

Computational modeling establishes mechanotransduction as a potent modulator of the mammalian circadian clockSemantic proximity Read

Lamins at the crossroads of mechanosignaling.Semantic proximity Read

The Dual Roles of Lamin A/C in Macrophage MechanotransductionSemantic proximity Read

The Fall of the Armor: Lamin Dysregulation and a Wide Network of Laminopathies.Semantic proximity Read

Structural and Mechanical Aberrations of the Nuclear Lamina in Disease.Semantic proximity Read

The circadian rhythm in intervertebral disc degeneration: an autophagy connectionSemantic proximity Read

Lamin A involvement in ageing processes.Semantic proximity Read

Broken nuclei--lamins, nuclear mechanics, and disease.Semantic proximity Read

Insight into the functional organization of nuclear lamins in health and disease.Semantic proximity Read

Lamin A/C as a Molecular Link Between Nuclear Organization, Chromatin Dynamics, and Tumor ProgressionSemantic proximity Read