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Group comparison based on genetic information reveals lineage-specific therapeutic vulnerabilities in acute myeloid leukemia

2023-06-13

Abstract excerpt

<title>Abstract</title> <p>Cancer is a genetic disease with specific mutations or fusions. Therapies targeting cancer cell-specific essential genes are expected to have efficient anticancer effects with fewer side effects. To explore such cancer cell-specific vulnerabilities, we established a two-group comparison system to predict essential genes in each cancer subtype using the data from the Cancer Dependency Ma...

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Literature Corpus work
5f44d062-d186-5c35-b285-7c30e23730b7
DOI
10.21203/rs.3.rs-3008101/v1
Open publication

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Group comparison based on genetic information reveals lineage-specific therapeutic vulnerabilities in acute myeloid leukemiaDOI 10.21203/rs.3.rs-3008101/v1
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