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Outcome prediction by the 2022 European LeukemiaNet genetic-risk classification for adults with acute myeloid leukemia: an Alliance study.

Leukemia - 1 Apr 2023

Mrózek Krzysztof, Kohlschmidt Jessica, Blachly James S, Nicolet Deedra, Carroll Andrew J, Archer Kellie J, Mims Alice S, Larkin Karilyn T, Orwick Shelley, Oakes Christopher C, Kolitz Jonathan E, Powell Bayard L, Blum William G, Marcucci Guido, Baer Maria R, Uy Geoffrey L, Stock Wendy, Byrd John C, Eisfeld Ann-Kathrin

Abstract excerpt

Recently, the European LeukemiaNet (ELN) revised its genetic-risk classification of acute myeloid leukemia (AML). We categorized 1637 adults with AML treated with cytarabine/anthracycline regimens according to the 2022 and 2017 ELN classifications. Compared with the 2017 ELN classification, 2022 favorable group decreased from 40% to 35% and adverse group increased from 37% to 41% of patients. The 2022...

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fms-Like Tyrosine Kinase 3
ELN gene
Leukemia, Myeloid, Acute
Mutation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Treatment Outcome

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Identifiers

PMID: 36823396
DOI: 10.1038/s41375-023-01846-8
PMCID: PMC10079544

Genes

ELN
NPM1
FLT3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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