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Article

Group comparison based on genetic information reveals lineage-specific therapeutic vulnerabilities in acute myeloid leukemia

2023-05-22

Abstract excerpt

<h4>ABSTRACT</h4> Cancer is a genetic disease with specific mutations or fusions. Therapies targeting cancer cell-specific essential genes are expected to have efficient anticancer effects with fewer side effects. To explore such cancer cell-specific vulnerabilities, we established a two-group comparison system to predict essential genes in each cancer subtype using the data from the Cancer Dependency Map (DepMap...

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Literature Corpus work
fcac150f-ff74-5615-a6ad-cdd248c16be5
DOI
10.1101/2023.05.18.541265
Open publication

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Group comparison based on genetic information reveals lineage-specific therapeutic vulnerabilities in acute myeloid leukemiaDOI 10.1101/2023.05.18.541265
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