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Experimental evolution of <i>Candida albicans</i> under hypoxia and heat shock reveals nuclear genome variants and mitochondrial methylome alterations

2017-07-22

Abstract excerpt

<h4>ABSTRACT</h4> Infection by Candida albicans requires its adaption to physical constraints in the human body, such as low oxygen tension (hypoxia), increased temperature (37°C) and different carbon sources. Previous studies demonstrated that the genetic variability of C. albicans isolates is an important adaptive mechanism, although little is known about the dynamics of this genetic diversity, and the influe...

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Literature Corpus work
5f0e3cfe-cd4e-5add-ad35-19e378c83744
DOI
10.1101/167338
Open publication

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