Article

Long-term benefit of immunotherapy in a patient with mismatch repair deficient/microsatellite instability-high/high tumor mutational burden lung cancer: case report and literature review

2022-09-28

Abstract excerpt

Genetic mutations that cause defective mismatch repair, may result in microsatellite instability, which is common in colorectal carcinoma and gastric cancers as well as Lynch syndrome. Mismatch repair deficiency/microsatellite instability-high(dMMR/MSI-H) predicts the tumor response to immune checkpoint inhibitors. However, few studies have evaluated the effects of immune checkpoint inhibitors on dMMR/MSI-H non-sm...

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Literature Corpus work: 5edd409d-be60-59ea-ba3d-c691badfa31b
DOI: 10.21203/rs.3.rs-2092664/v1

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