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Article

DNA mismatch repair deficiency in surgically resected lung adenocarcinoma: Microsatellite instability analysis using the Promega panel.

Lung cancer (Amsterdam, Netherlands) - 1 Aug 2017

Takamochi Kazuya, Takahashi Fumiyuki, Suehara Yoshiyuki, Sato Eiichi, Kohsaka Shinji, Hayashi Takuo, Kitano Shigehisa, Uneno Toshihide, Kojima Shinya, Takeuchi Kengo, Mano Hiroyuki, Suzuki Kenji

Abstract excerpt

OBJECTIVES: DNA mismatch repair (MMR) deficiency has recently received increasing attention as a significant biomarker to predict the treatment effect of immune checkpoint inhibitors for various malignant neoplasms. To evaluate MMR status, we analyzed the microsatellite instability (MSI) of lung adenocarcinomas. MATERIALS AND METHODS: Frozen tissues of lung adenocarcinoma and corresponding normal lung were...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 28676214
DOI: 10.1016/j.lungcan.2017.05.016

Genes

MLH1
ALK
EGFR
KRAS
RET
ROS1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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