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<i>Plasmodium falciparum</i> artemisinin-resistant K13 mutations confer a sexual-stage transmission advantage that can be overcome with atovaquone-proguanil

2020-10-27

Abstract excerpt

<h4>ABSTRACT</h4> Containing the spread of artemisinin (ART)-resistant Plasmodium falciparum will be assisted by improved understanding of its human-to-mosquito transmission. We compared gametocyte dynamics among field isolates containing K13 mutations conferring ART resistance and K13 wild-type parasites. In Pailin, Cambodia, the male to female gametocyte ratio was higher among K13 mutant infections compared to K...

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Literature Corpus work
5ec38b7c-9d22-5980-ab11-6be3e8ad951f
DOI
10.1101/2020.10.26.20214619
Open publication

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