Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Gametocyte production and transmission fitness of African and Asian Plasmodium falciparum isolates with differential susceptibility to artemisinins.

Antimicrobial agents and chemotherapy - 4 Jun 2025

Proellochs Nicholas I, Andolina Chiara, Ramjith Jordache, Stoter Rianne, van Gemert Geert-Jan, Graumans Wouter, Campino Susana, Vanheer Leen N, Okitwi Martin, Tumwebaze Patrick K, Conrad Melissa D, Clark Taane G, Fidock David A, Ménard Didier, Mok Sachel, Bousema Teun

Abstract excerpt

The emergence of Plasmodium falciparum parasites partially resistant to artemisinins (ART-R) poses a significant threat to recent gains in malaria control. ART-R has been associated with PfKelch13 (K13) mutations, which differ in fitness costs. This study investigates the gametocyte production and transmission fitness of African and Asian P. falciparum isolates with different K13 genotypes across multiple...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Africa
Share to Anopheles

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Antimalarials

Share to Artemisinins

Share to Drug Resistance

Share to Malaria, Falciparum

Share to Mosquito Vectors

Share to Plasmodium falciparum

Source

Open in PubMed Open full text

Identifiers

PMID: 40261068
DOI: 10.1128/aac.01930-24
PMCID: PMC12135531

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 9 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Gametocyte production and transmission fitness of African and Asian Plasmodium falciparum isolates with differential susceptibility to artemisinins.PMID 40261068Read ↗

<i>Plasmodium falciparum</i> artemisinin-resistant K13 mutations confer a sexual-stage transmission advantage that can be overcome with atovaquone-proguanilSemantic proximity Read ↗

Measuring Growth, Resistance, and Recovery after Artemisinin Treatment of Plasmodium falciparum in a single semi-high-throughput AssaySemantic proximity Read ↗

A portfolio of geographically distinct laboratory-adapted Plasmodium falciparum clones with consistent infection rates in Anopheles mosquitoesSemantic proximity Read ↗

Artemisinin-resistant malaria parasites show enhanced transmission to mosquitoes under drug pressureSemantic proximity Read ↗

A Portfolio of Geographically Distinct Laboratory-adapted Plasmodium Falciparum Clones With Consistent Infection Rates in Anopheles MosquitoesSemantic proximity Read ↗

Artemisinin-resistant Plasmodium falciparum clinical isolates can infect diverse mosquito vectors of Southeast Asia and AfricaSemantic proximity Read ↗

Artemisinin-Resistant Plasmodium falciparum with High Survival Rates, Uganda, 2014-2016.Semantic proximity Read ↗

Fitness of artemisinin-resistant Plasmodium falciparum in vitro.Semantic proximity Read ↗

Flow Cytometry-Based Analysis of Artemisinin-Resistant Plasmodium falciparum in the Ring-Stage Survival AssaySemantic proximity Read ↗

In vitro growth competition experiments that suggest consequences of the substandard artemisinin epidemic that may be accelerating drug resistance in P. falciparum malariaSemantic proximity Read ↗

Artemisinin-resistant Plasmodium falciparum parasites exhibit altered patterns of development in infected erythrocytes.Semantic proximity Read ↗

Multiple Phenotypic and Genotypic Artemisinin Sensitivity Evaluation of Malian Plasmodium falciparum Isolates.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.