Article

Activated-memory T cells influence naive T cell fate: A novel non-cytotoxic function of human CD8 T cells

2022-05-13

Abstract excerpt

<title>Abstract</title> <p>T cells are endowed with the capacity to sense their environment including other T cells around them. They do so to set their numbers and activation thresholds. This form of regulation has been well-studied within a given T cell population – i.e., within the naïve or memory pool; however, less is known about the cross-talk between T cell subsets. Here, we tested whether memory T cells i...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 5e822040-fb6f-588a-af55-86338b380a80
DOI: 10.21203/rs.3.rs-1651269/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Activated-memory T cells influence naive T cell fate: A novel non-cytotoxic function of human CD8 T cellsDOI 10.21203/rs.3.rs-1651269/v1Read

Rapid Recall Ability of Memory T cells is Encoded in their EpigenomeSemantic proximity Read

Atypical Human Effector/Memory CD4+ T Cells With a Naive-Like PhenotypeSemantic proximity Read

Precursor central memory versus effector cell fate and naïve CD4+ T cell heterogeneitySemantic proximity Read

The memory of a killer T cell: models of CD8(+) T cell differentiation.Semantic proximity Read

Delineation of a molecularly distinct terminally differentiated memory CD8 T cell populationSemantic proximity Read

A distinct subset of stem-cell memory is poised for the cytotoxicity program in CD4+ T cells in humans.Semantic proximity Read

Flexible and scalable control of T cell memory by a reversible epigenetic switchSemantic proximity Read

Single-cell transcriptomic and TCR analysis of human Cytomegalovirus (hCMV)-specific memory T cells reveals effector and pre-effectors of CD8 <sup>+</sup> - and CD4 <sup>+</sup> -cytotoxic T cellsSemantic proximity Read

A dynamic activation–memory cycle organizes the human IgG⁺ memory B cell compartmentSemantic proximity Read

Striking a Balance—Cellular and Molecular Drivers of Memory T Cell Development and Responses to Chronic StimulationSemantic proximity Read

Infection History Determines the Differentiation State of Human CD8 <sup>+</sup> T CellsSemantic proximity Read

Cytotoxic CD8+ Temra cells show loss of chromatin accessibility at genes associated with T cell activationSemantic proximity Read