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Hemoglobin as a peroxidase and drug target for oxidative stress-related diseases

2024-05-22

Abstract excerpt

<h4>Summary paragraph</h4> Hemoglobin (Hb) is well-known for transporting oxygen in red blood cells within blood vessels 1 . Although Hb is also present in the brain 2 , its role remains poorly understood. Here, we show that Hb, found in astrocytes of neurodegenerative animal models and patients, displays significant antioxidant effects through its H 2 O 2 -decomposing peroxidase activity, and a small molecul...

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Literature Corpus work
4d194b9f-4007-5444-869d-f15d518e0a86
DOI
10.1101/2024.05.21.594979
Open publication

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Hemoglobin as a peroxidase and drug target for oxidative stress-related diseasesDOI 10.1101/2024.05.21.594979
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