Article

Rhodanese Rdl2 produces reactive sulfur species to scavenge hydroxyl radical and protect mitochondria

2021-07-19

Abstract excerpt

During aerobic respiration, mitochondria generate superoxide anion (O 2 •− ), hydrogen peroxide (H 2 O 2 ), and hydroxyl radical (HO • ), and these reactive oxygen species (ROS) are detrimental to mitochondria. Mitochondrial damage is linked to a broad spectrum of pathologies such as Alzheimer’s disease, hemochromatosis, and diabetes. Mitochondria contain several enzymes for rapidly removing superoxide anion a...

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Literature Corpus work: 540fbe0b-6dbd-5f58-9bfc-8f011aa41159
DOI: 10.1101/2021.07.19.452856

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