Article
Carving the senescent phenotype by the chemical reactivity of catecholamines: An integrative review.
Ageing research reviews - 1 Mar 2022
Golubev Aleksei G
Abstract excerpt
Macromolecules damaged by covalent modifications produced by chemically reactive metabolites accumulate in the slowly renewable components of living bodies and compromise their functions. Among such metabolites, catecholamines (CA) are unique, compared with the ubiquitous oxygen, ROS, glucose and methylglyoxal, in that their high chemical reactivity is confined to a limited set of cell types, including the...
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