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A poly(A) isoform–aware single-cell and spatial atlas defines fibroblast niches in the human bladder

2025-12-18

Abstract excerpt

Bladder function relies on coordinated interactions among epithelial, stromal, vascular, and neural compartments, but high-resolution molecular and spatial features remain undefined. We generated a publicly accessible, poly(A) isoform–aware single-nucleus and spatial reference of the adult human bladder spanning four anatomical regions and both sexes. Integrating 74,694 snRNA-seq profiles with 168,476 Xenium-resol...

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Literature Corpus work
5e1e5eba-7ca5-59ac-b26c-4d1378e9bf7a
DOI
10.64898/2025.12.18.695268
Open publication

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A poly(A) isoform–aware single-cell and spatial atlas defines fibroblast niches in the human bladderDOI 10.64898/2025.12.18.695268
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