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Article

Systematic evaluation of single-cell multimodal data integration for comprehensive human reference atlas

2025-03-06

Abstract excerpt

The integration of multimodal single-cell data enables comprehensive organ reference atlases, yet its impact remains largely unexplored, particularly in complex tissues. We generated a benchmarking dataset for the renal cortex by integrating 3’ and 5’ scRNA-seq with joint snRNA-seq and snATAC-seq, profiling 119,744 high-quality nuclei/cells from 19 donors. To align cell identities and enable consistent comparisons...

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Literature Corpus work
76188df8-90e8-57b6-9654-2c7a90b788a1
DOI
10.1101/2025.03.06.637075
Open publication

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Systematic evaluation of single-cell multimodal data integration for comprehensive human reference atlasDOI 10.1101/2025.03.06.637075
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