Article

Germline <i>de novo</i> mutation rate of the highly heterozygous amphioxus genome

2025-07-18

Abstract excerpt

Germline de novo mutations (DNMs) are the ultimate source of heritable variation, yet their patterns in highly heterozygous genomes remain poorly understood. Amphioxus, an early-branching chordate with exceptionally high genomic heterozygosity (3.2∼4.2% in sequenced species), offers a unique model to explore mutational dynamics in such contexts. It is unclear whether high heterozygosity in amphioxus is due to a l...

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Literature Corpus work: 5e142a13-b0b1-50ad-9e1a-78ec690f3ce7
DOI: 10.1101/2025.07.14.664012

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