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Article

Direct estimation of de novo mutation rates in a chimpanzee parent-offspring trio by ultra-deep whole genome sequencing.

Scientific reports - 1 Nov 2017

Tatsumoto Shoji, Go Yasuhiro, Fukuta Kentaro, Noguchi Hideki, Hayakawa Takashi, Tomonaga Masaki, Hirai Hirohisa, Matsuzawa Tetsuro, Agata Kiyokazu, Fujiyama Asao

Abstract excerpt

Mutations generate genetic variation and are a major driving force of evolution. Therefore, examining mutation rates and modes are essential for understanding the genetic basis of the physiology and evolution of organisms. Here, we aim to identify germline de novo mutations through the whole-genome surveyance of Mendelian inheritance error sites (MIEs), those not inherited through the Mendelian inheritance manner...

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PMID: 29093469
DOI: 10.1038/s41598-017-13919-7
PMCID: PMC5666008

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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