Article

Metadichol Drives NK Cell Maturation via A CD122/IL-15 Signaling Through NF-κB-Independent Pathways

2026-01-27

Abstract excerpt

<h4>Background: </h4> Natural killer (NK) cells are essential innate immune effectors with significant therapeutic potential in cancer immunotherapy. However, strategies to enhance NK cell maturation and effector function remain limited. Metadichol, a nano-emulsion of policosanol capable of modulating 49 nuclear receptors, has demonstrated immunomodulatory properties, yet its effects on NK cell developmental progr...

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Literature Corpus work: 5e13c160-62a1-5fdc-aa58-591c894d3be5
DOI: 10.20944/preprints202601.1990.v1

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