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Metadichol as a Coordinated Activator of Core Cellular Machinery. Part III—Metadichol Induces Selective Remodeling of Nuclear Pore Complex Gene Expression in Human Peripheral Blood Mononuclear Cells: A Comprehensive Quantitative RT-PCR Analysis

2026-06-09

Abstract excerpt

<h4>Background: </h4> The nuclear pore complex (NPC) serves as the sole gateway for macromolecular exchange between the nucleus and cytoplasm, and its ~30 constituent nucleoporin (NUP) proteins are critical regulators of gene expression, immune function, and cellular identity. Metadichol, a nano-emulsion of long-chain polycosanols, exhibits pleiotropic biological activities including immunomodulatory and transcrip...

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Literature Corpus work: 43207938-43ea-5567-a0a3-7ce3a3d86a58
DOI: 10.20944/preprints202606.0691.v1

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