Article

Metadichol-Induced KLF Expression in PBMC Cells. Links SIRTs, NRs, TLRs, and Circadian genes. A Systems-Wide Biology Approach

2025-02-05

Abstract excerpt

Metadichol expresses all nuclear receptors, the TLR family (1-10), the Sirtuin family (1-7), all 48 nuclear receptors, and all Yamanaka factors: Oct 4, Sox2, KLF4, C-myc, and circadian genes: Per1, CRY1, BMAL1, CLOCK, and PPARGC1A. The transcription factor family Kruppel-like factors (KLFs) is essential for cell proliferation, differentiation, and development. Our tiny chemical, Metadichol, a long-chain lipid alco...

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Literature Corpus work: d623884e-6fad-5297-9d8f-2d707cd9023f
DOI: 10.20944/preprints202502.0271.v1

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