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Hierarchical Bayesian modeling identifies key considerations in the development of quantitative loop-mediated isothermal amplification assays

2023-01-19

Abstract excerpt

<h4>Motivation</h4> Loop-mediated isothermal amplification (LAMP) is a rapidly growing, fast, and cost-effective technique for detection of DNA/RNA in point-of-care biomedical applications. However, it remains unclear what factors affect LAMP’s quantitative resolution, and experimental optimization of primers presents a major bottleneck in assay design. A lack of model-based frameworks to characterize LAMP data a...

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Literature Corpus work
a1961386-6ce9-58a2-b1ec-c9e61b565723
DOI
10.1101/2023.01.16.524143
Open publication

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Hierarchical Bayesian modeling identifies key considerations in the development of quantitative loop-mediated isothermal amplification assaysDOI 10.1101/2023.01.16.524143
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