Article

Neuronal lipolysis participates in PUFA-mediated neural function and neurodegeneration

2020-02-14

Abstract excerpt

Lipid droplets (LDs) are dynamic cytoplasmic organelles present in most eukaryotic cells. The appearance of LDs in neurons is not usually observed under physiological conditions, but is associated with neural diseases. It remains unclear how LD dynamics is regulated in neurons and how the appearance of LDs affects neuronal functions. We discovered that mutations of two key lipolysis genes atgl-1 and lid-1 lead t...

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Literature Corpus work: 5ddf1bd0-c298-51fe-b532-de3b27760ade
DOI: 10.1101/2020.02.13.948430

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