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Article

Dopey-dependent regulation of extracellular vesicles maintains neuronal morphology.

Current biology : CB - 4 Nov 2024

Park Seungmee, Noblett Nathaniel, Pitts Lauren, Colavita Antonio, Wehman Ann M, Jin Yishi, Chisholm Andrew D

Abstract excerpt

Mature neurons maintain their distinctive morphology for extended periods in adult life. Compared to developmental neurite outgrowth, axon guidance, and target selection, relatively little is known of mechanisms that maintain the morphology of mature neurons. Loss of function in C. elegans dip-2, a member of the conserved lipid metabolic regulator Dip2 family, results in progressive overgrowth of neurites in...

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PMID: 39378880
DOI: 10.1016/j.cub.2024.09.018
PMCID: PMC11537831

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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